All functions |
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ADTnorm normalization to remove the technical variations across samples for each ADT marker. |
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arcsinh transformation. |
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A matrix of raw count for the cell by ADT markers |
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A matrix of raw count for the cell by features |
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Clean ADT marker name |
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Identify the valley outliers and impute by valley by closet neighbors. |
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Prompt Shiny browser to manually customize peaks and valleys locations. |
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Find the closest neighbors to impute outlier valleys. |
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Get the peak landmarks location using the peak region midpoint |
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Get the peak landmarks location using the peak mode |
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Get the valley landmark locations. |
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Merge locations of peak and valley landmarks |
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Load saved landmarks into a list of matrices, as required for input into "override_landmark". |
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Align the peak and valley landmarks by the warpset function |
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Plot the expression density profile for ONE ADT marker |
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Plot ADT marker expression density profile with identified peak and valley locations |
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Plot the expression density profile for ONE ADT marker with identified peak and valley locations |