All functions

ADTnorm()

ADTnorm normalization to remove the technical variations across samples for each ADT marker.

arcsinh_transform()

arcsinh transformation.

cell_x_adt

A matrix of raw count for the cell by ADT markers

cell_x_feature

A matrix of raw count for the cell by features

clean_adt_name()

Clean ADT marker name

detect_impute_outlier_valley()

Identify the valley outliers and impute by valley by closet neighbors.

get_customize_landmark()

Prompt Shiny browser to manually customize peaks and valleys locations.

get_neighbors()

Find the closest neighbors to impute outlier valleys.

get_peak_midpoint()

Get the peak landmarks location using the peak region midpoint

get_peak_mode()

Get the peak landmarks location using the peak mode

get_valley_location()

Get the valley landmark locations.

landmark_fill_na()

Merge locations of peak and valley landmarks

load_landmarks()

Load saved landmarks into a list of matrices, as required for input into "override_landmark".

peak_alignment()

Align the peak and valley landmarks by the warpset function

plot_adt_density_each()

Plot the expression density profile for ONE ADT marker

plot_adt_density_with_peak_valley()

Plot ADT marker expression density profile with identified peak and valley locations

plot_adt_density_with_peak_valley_each()

Plot the expression density profile for ONE ADT marker with identified peak and valley locations