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High-throughput, high sensitivity mapping of human T cell and CAR-T cell epigenomic landscapes underscores the role of H3K27me3 in subset differences and therapeutic outcomes
Fiorenza S+, Zheng Y+, Sarthy J, Sheih AS, Wu Q, Hirayama AV, Kimble EL, Kirchmeier D, Gottardo R, Henikoff S, Turtle CJ
Code
High-throughput, high sensitivity mapping of human T cell and CAR-T cell epigenomic landscapes underscores the role of H3K27me3 in subset differences and therapeutic outcomes
Robust Normalization and Integration of Single-cell Protein Expression across CITE-seq Datasets
CITE-seq technology enables the direct measurement of protein expression, known as antibody-derived tags (ADT), in addition to RNA …
Zheng Y, Seong-Hwan J, Conn D, Kim J, Tian Y, Florian M, Gottardo R
PDF Code DOI
Robust Normalization and Integration of Single-cell Protein Expression across CITE-seq Datasets
Normalization and De-noising of Single-cell Hi-C Data with BandNorm and scVI-3D
Single-cell high-throughput chromatin conformation capture methodologies (scHi-C) enable profiling long-range genomic interactions; …
Zheng Y+, Shen S+, Keleş S
PDF Code DOI
Normalization and De-noising of Single-cell Hi-C Data with BandNorm and scVI-3D
TreeHiC: Hierarchical Testing for Differential Chromatin Interactions.
Hi-C sequencing technology provides key insights into the 3D structures of the human genome. Although peak detection from Hi-C …
Duy Nguyen, Ye Zheng(co-first author), Sündüz Keleş
Sep 2, 2018
Cite Code Project
TreeHiC: Hierarchical Testing for Differential Chromatin Interactions.